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2005 study found that sildenafil did not significantly increase IELT. 2007 study concluded that sildenafil is a “very effective and safe” treatment for PE and can increase IELT. As the dosage increased, these men took longer to ejaculate, suggesting that Sertraline is a potentially viable treatment for premature ejaculation. double-blind test evaluated the effectiveness of Lexapro in the treatment of premature ejaculation. However, some doctors prescribe it off-label to stop premature ejaculation.

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